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    HomeMedication GuideBenzonatate Safety
    Antitussive

    Benzonatate: What to Know Before You Take It

    Also sold as Tessalon

    What Benzonatate Is Used For

    INDICATIONS AND USAGE Benzonatate Capsule is indicated for the symptomatic relief of cough.

    Warnings

    WARNINGS Hypersensitivity Severe hypersensitivity reactions (including bronchospasm, laryngospasm and cardiovascular collapse) have been reported which are possibly related to local anesthesia from sucking or chewing the capsule instead of swallowing it. Severe reactions have required intervention with vasopressor agents and supportive measures. Psychiatric Effects Isolated instances of bizarre behavior, including mental confusion and visual hallucinations, have also been reported in patients taking Benzonatate Capsule in combination with other prescribed drugs. Accidental Ingestion and Death in Children Keep Benzonatate Capsules out of reach of children. Accidental ingestion of Benzonatate Capsules resulting in death has been reported in children below age 10. Signs and symptoms of overdose have been reported within 15-20 minutes and death has been reported within one hour of ingestion. If accidental ingestion occurs, seek medical attention immediately (see OVERDOSAGE ).

    Contraindications

    CONTRAINDICATIONS Hypersensitivity to benzonatate or related compounds.

    Most-Reported Side Effects

    Based on 15,958 reports in the FDA Adverse Event Reporting System (FAERS). Reports do not prove the drug caused the effect.

    chronic kidney disease1,233fatigue1,219cough1,185dyspnoea1,138pneumonia1,100diarrhoea1,079nausea1,059pain918renal failure871death828headache813acute kidney injury797

    Explore full Benzonatate safety data in our free FDA Safety Explorer

    FDA Recalls (4)

    Class IIIOngoingDec 26, 2023

    Superpotent drug: Assay results were slightly above specification at the time zero point.

    Recalling firm: Amerisource Health Services LLC

    Class IIITerminatedMay 9, 2017

    Failed Stability Specifications: Out of Specification results obtained for preservative Methylparaben content.

    Recalling firm: Strides Pharma INC

    Class IITerminatedJan 6, 2015

    Failed Tablet/Capsule Specifications; recall initiated by manufacturer due to reports of wet capsules

    Recalling firm: American Health Packaging

    Class IITerminatedDec 23, 2014

    Failed Tablet/Capsule Specifications: Recall due to wet and/or leaking capsules.

    Recalling firm: Zydus Pharmaceuticals USA Inc

    This information is educational — not medical advice.

    This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.

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