Bremelanotide / Oxytocin / Tadalafil Blend: Patient Information & Safety Notes
Also known as BOT troche blend
Other names: bot-troche-blend, sexual-wellness-troche
A proprietary compounded sublingual troche combining bremelanotide (PT-141, FDA-approved for HSDD in premenopausal women), oxytocin (FDA-approved for obstetric use), and tadalafil (FDA-approved PDE5 inhibitor for ED/BPH). Each component has its own FDA-approved indication, but the combination product is not FDA-approved.
In plain language
What Bremelanotide With Oxytocin And Tadalafil Sublingual Blend is used for
- Sexual desire, arousal, and erectile function support (compounded blend)
Taking this medicine
How it is administered
- Sublingual troche
What's in it
Ingredients
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Risks and precautions
Risks and warnings
- Nausea, headaches, flushing, dizziness
- Blood pressure drop — especially dangerous with nitrates (tadalafil component)
Who should not take it
- Nitrate use (absolute contraindication due to tadalafil — potentially fatal hypotension)
- Blood pressure-lowering medications (significant risk)
- Pregnancy
Common questions
Patient questions
Can I take this blend if I use nitroglycerin?
No. This blend contains tadalafil (a PDE5 inhibitor), which is absolutely contraindicated with any nitrate medication including nitroglycerin, isosorbide, and recreational nitrites. Combining them can cause severe, potentially fatal hypotension.
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This information is educational — not medical advice.
This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.
Sources & References
Learn more about where our data comes from and how we write and review medical content.