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    HomeMedication GuideCholecalciferol safety
    Vitamin D supplement

    Cholecalciferol: What to Know Before You Take It

    Also known as D3

    A patient-focused safety profile with information from public regulatory sources.

    Reviewed by the OmniRx Health clinical team•Last reviewed Jul 4, 2026

    FDA boxed warning

    WARNING: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In case of accidental overdose, call a doctor or poison control center immediately.

    In plain language

    What Cholecalciferol is used for

    INDICATIONS: PNV-DHA is a multivitamin/multimineral nutritional supplement indicated for use in the dietary management of patients with nutritional deficiencies or are in need of nutritional supplementation.

    Read before you decide

    Risks and precautions

    Risks and warnings

    WARNING: Ingestion of more than 3 grams of omega-3 fatty acids (such as DHA) per day has been shown to have potential antithrombotic effects, including an increased bleeding time and International Normalized Ratio (INR). Administration of omega-3 fatty acids should be avoided in patients taking anticoagulants and in those known to have an inherited or acquired predisposition to bleeding.

    Who should not take it

    CONTRAINDICATIONS: This product is contraindicated in patients with a known hypersensitivity to any of the ingredients.

    Medication review

    Cholecalciferol drug interactions

    Check this against your full medication list in the Interaction Checker

    FDA safety data

    Most-reported side effects

    Based on 3,172 FAERS reports. Reports do not prove the drug caused the effect.

    femur fracture 1,406fall 820osteoarthritis 654low turnover osteopathy 617hypertension 559arthralgia 480gastrooesophageal reflux disease 442osteoporosis 434intramedullary rod insertion 429anxiety 414depression 414pain in extremity 403
    Explore full FDA safety data

    Common questions

    Patient questions

    What is Cholecalciferol prescribed for?

    INDICATIONS: PNV-DHA is a multivitamin/multimineral nutritional supplement indicated for use in the dietary management of patients with nutritional deficiencies or are in need of nutritional supplementation.

    What are the key warnings and safety precautions for Cholecalciferol?

    WARNING: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In case of accidental overdose, call a doctor or poison control center immediately.

    Does Cholecalciferol interact with other medications or foods?

    Cholecalciferol has 3 documented drug interaction(s) and 0 food interaction(s) in clinical databases. Always provide your complete medication list to your clinician.

    This information is educational — not medical advice.

    This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.

    Have medication questions?

    A licensed OmniRx provider can review your health history and medication list. Availability and treatment options are determined individually.