Cholecalciferol: What to Know Before You Take It

Also sold as D3

FDA Boxed Warning

WARNING: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In case of accidental overdose, call a doctor or poison control center immediately.

What Cholecalciferol Is Used For

INDICATIONS: PNV-DHA is a multivitamin/multimineral nutritional supplement indicated for use in the dietary management of patients with nutritional deficiencies or are in need of nutritional supplementation.

Warnings

WARNING: Ingestion of more than 3 grams of omega-3 fatty acids (such as DHA) per day has been shown to have potential antithrombotic effects, including an increased bleeding time and International Normalized Ratio (INR). Administration of omega-3 fatty acids should be avoided in patients taking anticoagulants and in those known to have an inherited or acquired predisposition to bleeding.

Contraindications

CONTRAINDICATIONS: This product is contraindicated in patients with a known hypersensitivity to any of the ingredients.

Cholecalciferol Drug Interactions (3)

Cholecalciferol + Ferrous Sulfate

WARNING: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6.

Moderate interaction

Cholecalciferol + Phenytoin

Warfarin Increased and decreased PT/INR responses have been reported when phenytoin is coadministered with warfarin Other Corticosteroids, doxycycline, estrogens, furosemide, oral contraceptives, paroxetine, quinidine, rifampin, sertraline, theophylline, and vitamin D Drugs whose level is decreased by phenytoin Antiepileptic drugs a Carbamazepine, felbamate, lamotrigine, topiramate, oxcarbazepine Antilipidemic agents Atorvastatin, fluvastatin, simvastatin Antiviral agents Efavirenz, lopinavir…

Moderate interaction

Cholecalciferol + Alendronate

Other disorders affecting mineral metabolism (such as vitamin D deficiency) should also be effectively treated.

Minor interaction

Check Cholecalciferol against your full medication list in our free Interaction Checker

Most-Reported Side Effects

Based on 3,172 reports in the FDA Adverse Event Reporting System (FAERS). Reports do not prove the drug caused the effect.

femur fracture1,406fall820osteoarthritis654low turnover osteopathy617hypertension559arthralgia480gastrooesophageal reflux disease442osteoporosis434intramedullary rod insertion429anxiety414depression414pain in extremity403

Explore full Cholecalciferol safety data in our free FDA Safety Explorer

This information is educational — not medical advice.

This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.

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