Melanotan II: Patient Information & Safety Notes
Also known as MT-II, MT2
Other names: mt-ii, mt2
Melanotan II is a synthetic alpha-MSH analogue that activates several melanocortin receptors. It is promoted online for tanning and other effects, but it is not approved by the FDA and carries significant safety concerns.
In plain language
What Melanotan II is used for
- NOT recommended. Investigated in research settings for pigmentation and appetite effects. Not a recognized medical treatment.
Taking this medicine
How it is administered
- Subcutaneous injection (research use)
Read before you decide
Risks and precautions
Risks and warnings
- Facial flushing
- Nausea and vomiting
- Spontaneous erections in males
- Darkening of existing moles and potential for new nevi — melanoma risk concerns
- Cardiovascular effects (blood pressure changes)
- Not established as safe
Who should not take it
- Pregnancy or breastfeeding
- History of melanoma or suspicious skin lesions
- Cardiovascular disease
Common questions
Patient questions
Is Melanotan II safe for tanning?
No. Melanotan II is not approved for tanning or any other use. Regulatory agencies worldwide have raised concerns about its safety, including potential links to melanoma and serious cardiovascular effects. It is not an established or recommended treatment.
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This information is educational — not medical advice.
This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.
Sources & References
Learn more about where our data comes from and how we write and review medical content.