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    HomeMedication GuideMelatonin safety
    Sleep supplement

    Melatonin: What to Know Before You Take It

    A patient-focused safety profile with information from public regulatory sources.

    Reviewed by the OmniRx Health clinical team•Last reviewed Jul 4, 2026

    In plain language

    What Melatonin is used for

    USES TAKE 15 MINUTES BEFORE MEALS

    Read before you decide

    Risks and precautions

    Risks and warnings

    WARNINGS Stop use and ask doctor if symptoms persist more than 5 days. If pregnant or breast-feeding ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Contains ethyl alcohol 30%

    FDA safety data

    Most-reported side effects

    Based on 53,113 FAERS reports. Reports do not prove the drug caused the effect.

    fatigue 4,352nausea 3,684off label use 3,342drug ineffective 3,160diarrhoea 2,960headache 2,899dyspnoea 2,522insomnia 2,487fall 2,386pain 2,318dizziness 2,299vomiting 2,172
    Explore full FDA safety data

    Common questions

    Patient questions

    What is Melatonin prescribed for?

    USES TAKE 15 MINUTES BEFORE MEALS

    What are the key warnings and safety precautions for Melatonin?

    WARNINGS Stop use and ask doctor if symptoms persist more than 5 days. If pregnant or breast-feeding ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Contains ethyl alcohol 30%

    Does Melatonin interact with other medications or foods?

    Melatonin has 0 documented drug interaction(s) and 0 food interaction(s) in clinical databases. Always provide your complete medication list to your clinician.

    This information is educational — not medical advice.

    This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.

    Have medication questions?

    A licensed OmniRx provider can review your health history and medication list. Availability and treatment options are determined individually.