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    HomeMedication GuideOxandrolone safety
    Anabolic-androgenic steroid (Schedule III controlled substance)Controlled Substance (Schedule III)

    Oxandrolone: Patient Information & Safety Notes

    Also known as Oxandrin, Anavar

    Other names: oxandrin, anavar

    Oxandrolone is an FDA-approved anabolic steroid used for weight gain after surgery, trauma, or chronic infection, and for bone pain associated with osteoporosis. It is a DEA Schedule III controlled substance.

    FDA-approved as Oxandrin for specific indications (weight gain after catabolic illness, bone pain in osteoporosis, short stature in Turner syndrome). It is a Schedule III controlled substance. Non-medical use for performance enhancement is illegal and prohibited in sport.
    Reviewed by the OmniRx Health clinical team•Last reviewed Jul 4, 2026

    In plain language

    What Oxandrolone is used for

    • FDA-approved: weight gain after surgery, infection, or trauma; bone pain (osteoporosis)
    • Off-label: muscle preservation in HIV wasting, burns

    Taking this medicine

    How it is administered

    • Oral tablet
    • Sublingual troche (compounded)

    Read before you decide

    Risks and precautions

    Risks and warnings

    • Fluid retention, edema
    • Acne
    • Hepatotoxicity (liver toxicity, especially at high doses)
    • Suppression of natural testosterone
    • Virilization in females (voice, clitoral changes)

    Who should not take it

    • Prostate cancer
    • Hypercalcemia (high blood calcium)
    • Advanced kidney disease
    • Pregnancy

    Common questions

    Patient questions

    Is oxandrolone (Anavar) safe for recreational use?

    No. Oxandrolone is a Schedule III controlled substance. Non-medical use is illegal. Misuse carries risks of liver damage, hormonal disruption, and cardiovascular effects. It requires a prescription from a DEA-licensed provider for approved indications.

    This information is educational — not medical advice.

    This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.