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    HomeMedication GuidePotassium Chloride Safety
    Electrolyte supplement

    Potassium Chloride: What to Know Before You Take It

    Also sold as Klor-Con, K-Tab

    What Potassium Chloride Is Used For

    1 INDICATIONS AND USAGE Potassium Chloride Extended-Release Tablets are indicated for the treatment and prophylaxis of hypokalemia with or without metabolic alkalosis, in patients for whom dietary management with potassium-rich foods or diuretic dose reduction is insufficient. Potassium Chloride Extended-Release Tablets are a potassium salt, indicated for the treatment and prophylaxis of hypokalemia with or without metabolic alkalosis in patients for whom dietary management with potassium-rich foods or diuretic dose reduction is insufficient. (1)

    Warnings

    5 WARNINGS AND PRECAUTIONS Gastrointestinal Irritation: Take with meals (5.1) 5.1 Gastrointestinal Adverse Reactions Solid oral dosage forms of potassium chloride can produce ulcerative and/or stenotic lesions of the gastrointestinal tract, particularly if the drug maintains contact with the gastrointestinal mucosa for prolonged periods. Consider the use of liquid potassium in patients with dysphagia, swallowing disorders, or severe gastrointestinal motility disorders. If severe vomiting, abdominal pain, distention, or gastrointestinal bleeding occurs, discontinue potassium chloride extended-release tablets and consider possibility of ulceration, obstruction or perforation. Potassium chloride extended-release tablets should not be taken on an empty stomach because of its potential for gastric irritation [see Dosage and Administration (2.1) ] .

    Contraindications

    4 CONTRAINDICATIONS Potassium chloride is contraindicated in patients on triamterene and amiloride. Concomitant use with triamterene and amiloride (4)

    Most-Reported Side Effects

    Based on 118,686 reports in the FDA Adverse Event Reporting System (FAERS). Reports do not prove the drug caused the effect.

    nausea8,825diarrhoea8,387dyspnoea8,223fatigue7,961vomiting6,487death5,712pneumonia5,461headache5,242asthenia5,214dizziness5,095pain5,000drug ineffective4,876

    Explore full Potassium Chloride safety data in our free FDA Safety Explorer

    FDA Recalls (showing 12 of 20)

    Class IOngoingApr 28, 2026

    Presence of Particulate Matter.

    Recalling firm: B BRAUN MEDICAL INC

    Class IIOngoingApr 2, 2026

    Lack of Assurance of Sterility; potential for leakage from the diaphragm port once the foil is removed.

    Recalling firm: B BRAUN MEDICAL INC

    Class IOngoingOct 29, 2025

    Labeling: Label Error on Declared Strength-The overwrap label may incorrectly identify the product as POTASSIUM CHLORIDE Inj. 10 mEq instead of POTASSIUM CHLORIDE Inj. 20 mEq

    Recalling firm: Otsuka ICU Medical LLC

    Class IOngoingOct 29, 2025

    Labeling: Label Error on Declared Strength-The overwrap label may incorrectly identify the product as POTASSIUM CHLORIDE Inj. 10 mEq instead of POTASSIUM CHLORIDE Inj. 20 mEq

    Recalling firm: Otsuka ICU Medical LLC

    Class IOngoingAug 18, 2025

    Presence of Particulate Matter

    Recalling firm: B BRAUN MEDICAL INC

    Class IIOngoingAug 4, 2025

    Lack of Assurance of Sterility; potential for fluid leakage at one of the weld sites.

    Recalling firm: B BRAUN MEDICAL INC

    Class IOngoingFeb 13, 2025

    Labeling: Label Error on Declared Strength. Overwrap labeled as Potassium Chloride Inj 10 mEq may contain flexible containers of Potassium Chloride Inj 20 mEq

    Recalling firm: ICU Medical, Inc.

    Class IOngoingFeb 13, 2025

    Labeling: Label Error on Declared Strength. Cases labeled POTASSIUM CHLORIDE 20 mEq, may contain flexible containers with overwrap mislabeled as 10 mEq. The correct dosage strength of 20 mEq is printed on the labeling affixed to the product flexible container.

    Recalling firm: ICU Medical, Inc.

    Class IIOngoingJan 30, 2025

    Failed Dissolution Specifications.

    Recalling firm: The Harvard Drug Group LLC dba Major Pharmaceuticals and Rugby Laboratories

    Class IIITerminatedJul 2, 2024

    Defective container: potential for non-sealed pouches which can lead to product leakage.

    Recalling firm: Novel Laboratories, Inc. d.b.a Lupin Somerset

    Class IOngoingJun 25, 2024

    Failed Dissolution Specifications

    Recalling firm: Amerisource Health Services LLC

    Class IIOngoingMay 30, 2024

    CGMP Deviations

    Recalling firm: Glenmark Pharmaceuticals Inc., USA

    This information is educational — not medical advice.

    This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.

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