How Alcohol with metronidazole Affects Your Medications
Avoid all alcohol (including some liquid medicines and mouthwashes that contain alcohol) while taking metronidazole and for at least 3 days after your last dose.
This interaction is generally considered major in severity.
How It Happens
Metronidazole can cause a disulfiram-like reaction with alcohol — flushing, nausea, vomiting, headache, and a fast heartbeat.
What to Do
Avoid all alcohol (including some liquid medicines and mouthwashes that contain alcohol) while taking metronidazole and for at least 3 days after your last dose.
Medication Classes Affected
Specific Medications to Watch
This information is educational — not medical advice.
This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.