How Coffee with levothyroxine Affects Your Medications
Take levothyroxine with water on an empty stomach and wait at least 30–60 minutes before coffee or breakfast. Keep the same routine every day so your levels stay steady.
This interaction is generally considered moderate in severity.
How It Happens
Drinking coffee too soon after taking levothyroxine can bind the medication in the gut and lower how much is absorbed, reducing its effect on your thyroid levels.
What to Do
Take levothyroxine with water on an empty stomach and wait at least 30–60 minutes before coffee or breakfast. Keep the same routine every day so your levels stay steady.
Medication Classes Affected
Specific Medications to Watch
This information is educational — not medical advice.
This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.
Sources & References
Learn more about where our data comes from and how we write and review medical content.