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    HomeMedication GuideFood & Drug InteractionsFood, coffee, and mineral water with oral bisphosphonates
    Food & Drink Interaction

    How Food, coffee, and mineral water with oral bisphosphonates Affects Your Medications

    Take alendronate first thing in the morning with a full glass of plain water, stay upright, and wait at least 30 minutes before eating, drinking, or taking other medicines.

    Moderate interaction

    This interaction is generally considered moderate in severity.

    How It Happens

    Anything other than plain water dramatically reduces absorption of oral bisphosphonates like alendronate.

    What to Do

    Take alendronate first thing in the morning with a full glass of plain water, stay upright, and wait at least 30 minutes before eating, drinking, or taking other medicines.

    Medication Classes Affected

    Bisphosphonates

    Specific Medications to Watch

    This information is educational — not medical advice.

    This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.

    Not Sure If This Applies to You?

    A licensed OmniRx provider can review your diet and medications together and give you guidance tailored to your situation.