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    HomeMedication Guide5-Amino-1-Methylquinolinium safety
    NNMT (nicotinamide N-methyltransferase) inhibitor — research compoundInvestigational / Not FDA-Approved

    5-Amino-1MQ: Patient Information & Safety Notes

    Other names: 5-amino-1-methylquinolinium, 5a1mq

    5-Amino-1MQ is a laboratory research compound that inhibits nicotinamide N-methyltransferase (NNMT). Preclinical studies have examined NNMT-related metabolic pathways, but there is no established human clinical evidence and it is not approved by the FDA.

    NOT FDA-approved. 5-Amino-1MQ exists primarily in preclinical (animal) research. Human safety and efficacy have not been established in peer-reviewed clinical trials. It is not a recognized medical treatment.
    Reviewed by the OmniRx Health clinical teamLast reviewed Jul 4, 2026

    In plain language

    What 5-Amino-1-Methylquinolinium is used for

    • Studied in laboratory and animal models of NNMT-related metabolic pathways

    Taking this medicine

    How it is administered

    • Oral capsule

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    Risks and precautions

    Risks and warnings

    • Insomnia if taken late in the day (reported anecdotally)
    • Human safety profile not established

    Who should not take it

    • Pregnancy or breastfeeding
    • History of myocardial infarction or atrial fibrillation (cardiovascular precaution)

    Common questions

    Patient questions

    Is 5-Amino-1MQ approved or safe?

    No. 5-Amino-1MQ is a research compound with no FDA approval and no established human clinical evidence of safety or effectiveness. Individuals interested in weight management should discuss FDA-approved options with a licensed provider.

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    This information is educational — not medical advice.

    This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.