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    HomeMedication GuideFerrous Sulfate Safety
    Oral iron supplement

    Ferrous Sulfate: What to Know Before You Take It

    Also sold as Feosol, Slow Fe

    What Ferrous Sulfate Is Used For

    Uses: See symptoms on front panel. Relieves hot flashes with headaches *

    Ferrous Sulfate Drug Interactions (8)

    Ferrous Sulfate + Carbidopa Levodopa
    7 DRUG INTERACTIONS Drugs metabolized by COMT: use with caution ( 5.11 , 7.2 ) Anti-hypertensive agents: dose adjustment may be required ( 7.3 ) Tricyclic antidepressants: risk of hypertension and dyskinesia reported during concomitant use with carbidopa/levodopa ( 7.4 ) Dopamine D2 receptor antagonists, isoniazid, phenytoin, papaverine and iron salts: may reduce efficacy of carbidopa, levodopa and entacapone tablets ( 7.5 , 7.6 , 7.7 , 7.8 , 7.9 ) Drugs that interfere with biliary excretion,…
    Moderate interaction
    Ferrous Sulfate + Cholecalciferol
    WARNING: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6.
    Moderate interaction
    Ferrous Sulfate + Levofloxacin
    Monitor prothrombin time, INR and watch for bleeding (7.2) Antidiabetic agents Carefully monitor blood glucose (5.13, 7.3) 7.1 Chelation Agents: Antacids, Sucralfate, Metal Cations, Multivitamins While the chelation by divalent cations is less marked than with other fluoroquinolones, concurrent administration of levofloxacin tablets with antacids containing magnesium, or aluminum, as well as sucralfate, metal cations such as iron, and multivitamin preparations with zinc may interfere with the…
    Moderate interaction
    Ferrous Sulfate + Carbamazepine
    Complete pretreatment blood counts, including platelets and possibly reticulocytes and serum iron, should be obtained as a baseline.
    Minor interaction
    Ferrous Sulfate + Doxycycline
    Absorption of tetracyclines is impaired by antacids containing aluminum, calcium, or magnesium, and iron-containing preparations.
    Minor interaction
    Ferrous Sulfate + Lansoprazole
    Drugs Dependent on Gastric pH for Absorption (e.g., iron salts, erlotinib, dasatinib, nilotinib, mycophenolate mofetil, ketoconazole/itraconazole) Clinical Impact: Lansoprazole can reduce the absorption of other drugs due to its effect on reducing intragastric acidity.
    Minor interaction
    Ferrous Sulfate + Levothyroxine
    Drug or Drug Class Effect Phosphate Binders (e.g., calcium carbonate, ferrous sulfate, sevelamer, lanthanum) Phosphate binders may bind to levothyroxine.
    Minor interaction
    Ferrous Sulfate + Pantoprazole
    Drugs Dependent on Gastric pH for Absorption (e.g., iron salts, erlotinib, dasatinib, nilotinib, mycophenolate mofetil, ketoconazole/itraconazole) Clinical Impact: Pantoprazole can reduce the absorption of other drugs due to its effect on reducing intragastric acidity.
    Minor interaction

    Check Ferrous Sulfate against your full medication list in our free Interaction Checker

    Most-Reported Side Effects

    Based on 48,897 reports in the FDA Adverse Event Reporting System (FAERS). Reports do not prove the drug caused the effect.

    fatigue3,424diarrhoea3,187nausea2,814dyspnoea2,807death2,393off label use2,375acute kidney injury2,093anaemia2,008headache1,996pneumonia1,990asthenia1,957pain1,938

    Explore full Ferrous Sulfate safety data in our free FDA Safety Explorer

    This information is educational — not medical advice.

    This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.

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