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    HomeMedication GuideFerrous Sulfate safety
    Oral iron supplement

    Ferrous Sulfate: What to Know Before You Take It

    Also known as Feosol, Slow Fe

    A patient-focused safety profile with information from public regulatory sources.

    Reviewed by the OmniRx Health clinical team•Last reviewed Jul 4, 2026

    In plain language

    What Ferrous Sulfate is used for

    Uses: See symptoms on front panel. Relieves hot flashes with headaches *

    Medication review

    Ferrous Sulfate drug interactions

    Ferrous Sulfate + Carbidopa Levodopa7 DRUG INTERACTIONS Drugs metabolized by COMT: use with caution ( 5.11 , 7.2 ) Anti-hypertensive agents: dose adjustment may be required ( 7.3 ) Tricyclic antidepressants: risk of hypertension and dyskinesia reported during concomitant use with carbidopa/levodopa ( 7.4 ) Dopamine D2 receptor antagonists, isoniazid, phenytoin, papaverine and iron salts: may reduce efficacy of carbidopa, levodopa and entacapone tablets ( 7.5 , 7.6 , 7.7 , 7.8 , 7.9 ) Drugs that interfere with biliary excretion,…Moderate interactionFerrous Sulfate + CholecalciferolWARNING: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6.Moderate interactionFerrous Sulfate + LevofloxacinMonitor prothrombin time, INR and watch for bleeding (7.2) Antidiabetic agents Carefully monitor blood glucose (5.13, 7.3) 7.1 Chelation Agents: Antacids, Sucralfate, Metal Cations, Multivitamins While the chelation by divalent cations is less marked than with other fluoroquinolones, concurrent administration of levofloxacin tablets with antacids containing magnesium, or aluminum, as well as sucralfate, metal cations such as iron, and multivitamin preparations with zinc may interfere with the…Moderate interactionFerrous Sulfate + CarbamazepineComplete pretreatment blood counts, including platelets and possibly reticulocytes and serum iron, should be obtained as a baseline.Minor interactionFerrous Sulfate + DoxycyclineAbsorption of tetracyclines is impaired by antacids containing aluminum, calcium, or magnesium, and iron-containing preparations.Minor interactionFerrous Sulfate + LansoprazoleDrugs Dependent on Gastric pH for Absorption (e.g., iron salts, erlotinib, dasatinib, nilotinib, mycophenolate mofetil, ketoconazole/itraconazole) Clinical Impact: Lansoprazole can reduce the absorption of other drugs due to its effect on reducing intragastric acidity.Minor interactionFerrous Sulfate + LevothyroxineDrug or Drug Class Effect Phosphate Binders (e.g., calcium carbonate, ferrous sulfate, sevelamer, lanthanum) Phosphate binders may bind to levothyroxine.Minor interactionFerrous Sulfate + PantoprazoleDrugs Dependent on Gastric pH for Absorption (e.g., iron salts, erlotinib, dasatinib, nilotinib, mycophenolate mofetil, ketoconazole/itraconazole) Clinical Impact: Pantoprazole can reduce the absorption of other drugs due to its effect on reducing intragastric acidity.Minor interaction
    Check this against your full medication list in the Interaction Checker

    FDA safety data

    Most-reported side effects

    Based on 48,897 FAERS reports. Reports do not prove the drug caused the effect.

    fatigue 3,424diarrhoea 3,187nausea 2,814dyspnoea 2,807death 2,393off label use 2,375acute kidney injury 2,093anaemia 2,008headache 1,996pneumonia 1,990asthenia 1,957pain 1,938
    Explore full FDA safety data

    Common questions

    Patient questions

    What is Ferrous Sulfate prescribed for?

    Uses: See symptoms on front panel. Relieves hot flashes with headaches *

    What are the key warnings and safety precautions for Ferrous Sulfate?

    Patients taking Ferrous Sulfate should be screened for contraindications, organ function, and concurrent medications by a licensed healthcare provider before beginning treatment.

    Does Ferrous Sulfate interact with other medications or foods?

    Ferrous Sulfate has 8 documented drug interaction(s) and 0 food interaction(s) in clinical databases. Always provide your complete medication list to your clinician.

    This information is educational — not medical advice.

    This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.

    Have medication questions?

    A licensed OmniRx provider can review your health history and medication list. Availability and treatment options are determined individually.

    Sources & References

    Learn more about where our data comes from and how we write and review medical content.