Kisspeptin: Patient Information & Safety Notes
Also known as Kiss1
Other names: kiss1, metastin, kisspeptin-10, kisspeptin-54
Kisspeptin is a naturally occurring neuropeptide produced in the hypothalamus that plays a central role in regulating the hormonal reproductive axis (HPG axis) by stimulating GnRH release. It has been studied in clinical trials for fertility and hypoactive sexual desire. It is not FDA-approved for general use.
In plain language
What Kisspeptin is used for
- Investigated for fertility support (LH/FSH stimulation)
- Investigated for hypoactive sexual desire disorder
Taking this medicine
How it is administered
- Subcutaneous injection
Read before you decide
Risks and precautions
Risks and warnings
- Flushing, nausea, acne
- Potential hormonal disruption if used inappropriately
Who should not take it
- Pregnancy
- Hormone-sensitive conditions (precautionary)
Common questions
Patient questions
Is kisspeptin FDA-approved?
No. Kisspeptin is not FDA-approved for any therapeutic indication. It is under clinical investigation for fertility and sexual desire. A licensed reproductive endocrinologist or provider should be consulted for evidence-based fertility treatments.
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This information is educational — not medical advice.
This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.
Sources & References
Learn more about where our data comes from and how we write and review medical content.