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    HomeMedication GuideOstarine safety
    Selective androgen receptor modulator (SARM) — investigationalInvestigational / Not FDA-Approved

    Ostarine (MK-2866): Patient Information & Safety Notes

    Also known as MK-2866, GTx-024

    Other names: mk-2866, enobosarm, gtx-024, -ostarine-mk2866

    Ostarine (enobosarm) is an investigational SARM that binds androgen receptors selectively in muscle and bone tissue. It has been in clinical trials for muscle wasting (cancer cachexia) but has NOT received FDA approval. SARMs as a class are not FDA-approved as drugs and are not legal dietary supplements.

    NOT FDA-approved. Ostarine is not an approved drug or legal dietary supplement. The FDA has warned consumers about SARMs in supplements, noting risks of liver injury, cardiovascular effects, and potential interference with normal hormonal function. Its sale as a supplement is illegal.
    Reviewed by the OmniRx Health clinical team•Last reviewed Jul 4, 2026

    In plain language

    What Ostarine is used for

    • Investigated in clinical trials for cancer cachexia and muscle wasting (no approved use)

    Taking this medicine

    How it is administered

    • Oral capsule

    Read before you decide

    Risks and precautions

    Risks and warnings

    • Fatigue, depression
    • Headache, nausea
    • Suppression of natural testosterone
    • Potential hepatotoxicity (liver injury)
    • Cardiovascular risk (lipid changes)

    Who should not take it

    • Pregnancy or breastfeeding
    • Liver disease

    Common questions

    Patient questions

    Are SARMs like ostarine legal?

    SARMs including ostarine are not FDA-approved and cannot legally be sold as dietary supplements. The FDA has issued multiple warnings about SARM products. Using them without medical supervision and a legitimate investigational protocol carries significant legal and health risks.

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    This information is educational — not medical advice.

    This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.