SS-31 (Elamipretide): Patient Information & Safety Notes
Also known as SS31, SS-31, MTP-131, Bendavia
Other names: ss-31, mtp-131, bendavia
SS-31 (elamipretide) is a synthetic cell-permeable tetrapeptide that targets the inner mitochondrial membrane, reducing oxidative stress and improving mitochondrial function. It has been studied in clinical trials for heart failure and Barth syndrome. It has not received FDA approval.
In plain language
What Elamipretide is used for
- Investigated in clinical trials for mitochondrial dysfunction, heart failure, and inherited metabolic disorders
Taking this medicine
How it is administered
- Subcutaneous injection
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Risks and precautions
Risks and warnings
- Injection site irritation
- Headaches, dizziness
Who should not take it
- History of bleeding disorder
- Pregnancy
- Age under 18 (insufficient data)
Common questions
Patient questions
Is SS-31 / elamipretide FDA-approved?
No. Elamipretide has Orphan Drug designation and has been in clinical trials, but has not received FDA approval for any indication. It is not an established treatment for general fatigue, aging, or exercise performance.
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This information is educational — not medical advice.
This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.
Sources & References
Learn more about where our data comes from and how we write and review medical content.