Does Atomoxetine Interact With Methylphenidate?
7.7 Methylphenidate Coadministration of methylphenidate with atomoxetine did not increase cardiovascular effects beyond those seen with methylphenidate alone.
Severity: Minor
Severity basis: drug interactions section. Combining Atomoxetine (Non-stimulant ADHD agent) and Methylphenidate (CNS stimulant (ADHD)) is classified as a minor interaction.
What to Do
This is generally a minor interaction, but review it with your pharmacist to be sure it is safe for you.
From the FDA Label
7.7 Methylphenidate Coadministration of methylphenidate with atomoxetine did not increase cardiovascular effects beyond those seen with methylphenidate alone.
Source: FDA structured product labeling (set_id 0782204e-56a3-4439-9fb8-194da9487049).
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This information is educational — not medical advice.
This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.
Other Atomoxetine Interactions
- Atomoxetine + Desvenlafaxine(moderate)
- Atomoxetine + Fluoxetine(moderate)
- Atomoxetine + Paroxetine(moderate)
- Atomoxetine + Albuterol(minor)
- Atomoxetine + Aspirin(minor)
- Atomoxetine + Celecoxib(minor)
- Atomoxetine + Diazepam(minor)
- Atomoxetine + Omeprazole(minor)
- Atomoxetine + Phenytoin(minor)
- Atomoxetine + Warfarin(minor)