Does Amoxicillin Clavulanate Interact With Estradiol?
Following administration of amoxicillin to pregnant women, a transient decrease in plasma concentration of total conjugated estriol, estriol-glucuronide, conjugated estrone, and estradiol has been noted.
Severity: Minor
Severity basis: drug interactions section. Combining Amoxicillin Clavulanate (Penicillin/beta-lactamase inhibitor antibiotic) and Estradiol (Estrogen) is classified as a minor interaction.
What to Do
This is generally a minor interaction, but review it with your pharmacist to be sure it is safe for you.
From the FDA Label
Following administration of amoxicillin to pregnant women, a transient decrease in plasma concentration of total conjugated estriol, estriol-glucuronide, conjugated estrone, and estradiol has been noted.
Source: FDA structured product labeling (set_id 04a31a42-d79e-bbb4-e063-6394a90a63ee).
Amoxicillin Clavulanate
Penicillin/beta-lactamase inhibitor antibiotic
Brands: Augmentin
View Amoxicillin Clavulanate safety profileCheck these against your full medication list in our free Interaction Checker
This information is educational — not medical advice.
This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.