Does Clonidine Interact With Insulin Glargine?
Drugs That May Increase or Decrease the Blood Glucose Lowering Effect of BASAGLAR Drugs: Alcohol, beta-blockers, clonidine, and lithium salts.
Severity: Moderate
Severity basis: drug interactions section (keywords: may increase). Combining Clonidine (Central alpha-2 agonist) and Insulin Glargine (Long-acting insulin) is classified as a moderate interaction.
What to Do
Use this combination with caution. Your prescriber may monitor you more closely or adjust doses.
From the FDA Label
Drugs That May Increase or Decrease the Blood Glucose Lowering Effect of BASAGLAR Drugs: Alcohol, beta-blockers, clonidine, and lithium salts.
Source: FDA structured product labeling (set_id 0ad21db3-2b1c-4ed9-a687-bdd6a74d0aae).
Insulin Glargine
Long-acting insulin
Brands: Lantus, Basaglar, Toujeo
View Insulin Glargine safety profileCheck these against your full medication list in our free Interaction Checker
This information is educational — not medical advice.
This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.
Other Clonidine Interactions
- Clonidine + Carvedilol(moderate)
- Clonidine + Insulin Aspart(moderate)
- Clonidine + Amiodarone(minor)
- Clonidine + Amitriptyline(minor)
- Clonidine + Atenolol(minor)
- Clonidine + Diltiazem(minor)
- Clonidine + Glimepiride(minor)
- Clonidine + Metoprolol(minor)
- Clonidine + Propranolol(minor)
- Clonidine + Verapamil(minor)