Does Carvedilol Interact With Clonidine?
( 7.1 , 7.5 ) Hypotensive agents (e.g., reserpine, MAO inhibitors, clonidine) may increase the risk of hypotension and/or severe bradycardia.
Severity: Moderate
Severity basis: drug interactions section (keywords: may increase). Combining Carvedilol (Beta-blocker) and Clonidine (Central alpha-2 agonist) is classified as a moderate interaction.
What to Do
Use this combination with caution. Your prescriber may monitor you more closely or adjust doses.
From the FDA Label
( 7.1 , 7.5 ) Hypotensive agents (e.g., reserpine, MAO inhibitors, clonidine) may increase the risk of hypotension and/or severe bradycardia.
Source: FDA structured product labeling (set_id 010290af-81f4-0037-e063-6394a90a4638).
Check these against your full medication list in our free Interaction Checker
This information is educational — not medical advice.
This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.
Other Carvedilol Interactions
Other Clonidine Interactions
- Clonidine + Insulin Aspart(moderate)
- Clonidine + Insulin Glargine(moderate)
- Clonidine + Amiodarone(minor)
- Clonidine + Amitriptyline(minor)
- Clonidine + Atenolol(minor)
- Clonidine + Diltiazem(minor)
- Clonidine + Glimepiride(minor)
- Clonidine + Metoprolol(minor)
- Clonidine + Propranolol(minor)
- Clonidine + Verapamil(minor)