Does Furosemide Interact With Meloxicam?
Diuretics Clinical Impact: Clinical studies, as well as post-marketing observations, showed that NSAIDs reduced the natriuretic effect of loop diuretics (e.g., furosemide) and thiazide diuretics in some patients.
Severity: Minor
Severity basis: drug interactions section. Combining Furosemide (Loop diuretic) and Meloxicam (Nonsteroidal anti-inflammatory drug (NSAID)) is classified as a minor interaction.
What to Do
This is generally a minor interaction, but review it with your pharmacist to be sure it is safe for you.
How This Interaction Works
Interactions like this one can happen when two medicines have overlapping effects, or when one changes how the other is absorbed, broken down, or cleared from the body. Furosemide is a loop diuretic and Meloxicam is a nonsteroidal anti-inflammatory drug (nsaid); together they are documented as a minor interaction. How much this matters depends on your dose, your other medications, and your overall health.
If You Take Both Medications
If you have been prescribed both Furosemide and Meloxicam, do not start, stop, or change either medication on your own — some medicines are unsafe to stop suddenly. Tell your prescriber and pharmacist that you take both so they can decide whether the combination is right for you, adjust the dose, monitor you more closely, or suggest an alternative.
From the FDA Label
Diuretics Clinical Impact: Clinical studies, as well as post-marketing observations, showed that NSAIDs reduced the natriuretic effect of loop diuretics (e.g., furosemide) and thiazide diuretics in some patients.
Source: FDA structured product labeling (set_id 06a401f0-4380-4081-86ed-a309a25abf6b).
Check these against your full medication list in our free Interaction Checker
Frequently Asked Questions
Can you take Furosemide and Meloxicam together?
Furosemide and Meloxicam have a documented minor interaction. This is generally a minor interaction, but review it with your pharmacist to be sure it is safe for you.
How serious is the Furosemide and Meloxicam interaction?
It is classified as a minor interaction, based on the FDA label's drug interactions section. A minor interaction is usually limited in effect but is still worth discussing with your care team.
What should I do if I'm taking both Furosemide and Meloxicam?
If you have been prescribed both Furosemide and Meloxicam, do not start, stop, or change either medication on your own — some medicines are unsafe to stop suddenly. Tell your prescriber and pharmacist that you take both so they can decide whether the combination is right for you, adjust the dose, monitor you more closely, or suggest an alternative.
This information is educational — not medical advice.
This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.
Other Furosemide Interactions
- Furosemide + Cyclosporine(moderate)
- Furosemide + Indomethacin(moderate)
- Furosemide + Methotrexate(moderate)
- Furosemide + Phenytoin(moderate)
- Furosemide + Sucralfate(moderate)
- Furosemide + Aspirin(minor)
- Furosemide + Atenolol(minor)
- Furosemide + Celecoxib(minor)
- Furosemide + Levothyroxine(minor)
- Furosemide + Liothyronine(minor)
- Furosemide + Lithium(minor)
- Furosemide + Naproxen(minor)
- Furosemide + Potassium Chloride(minor)
- Furosemide + Ramipril(minor)
- Furosemide + Risperidone(minor)
- Furosemide + Tamsulosin(minor)
Other Meloxicam Interactions
- Meloxicam + Aspirin(contraindicated)
- Meloxicam + Cyclosporine(moderate)
- Meloxicam + Methotrexate(moderate)
- Meloxicam + Warfarin(moderate)
- Meloxicam + Celecoxib(minor)
- Meloxicam + Fluconazole(minor)
- Meloxicam + Indomethacin(minor)
- Meloxicam + Itraconazole(minor)
- Meloxicam + Lithium(minor)
- Meloxicam + Naproxen(minor)
- Meloxicam + Propranolol(minor)