Does Meloxicam Interact With Naproxen?
In the absence of data regarding potential interaction between pemetrexed and NSAIDs with longer half-lives (e.g., meloxicam, nabumetone), patients taking these NSAIDs should interrupt dosing for at least five days before, the day of, and two days following pemetrexed administration.
Severity: Minor
Severity basis: drug interactions section. Combining Meloxicam (Nonsteroidal anti-inflammatory drug (NSAID)) and Naproxen (Nonsteroidal anti-inflammatory drug (NSAID)) is classified as a minor interaction.
What to Do
This is generally a minor interaction, but review it with your pharmacist to be sure it is safe for you.
From the FDA Label
In the absence of data regarding potential interaction between pemetrexed and NSAIDs with longer half-lives (e.g., meloxicam, nabumetone), patients taking these NSAIDs should interrupt dosing for at least five days before, the day of, and two days following pemetrexed administration.
Source: FDA structured product labeling (set_id 000155a8-709c-44e5-a75f-cd890f3a7caf).
Naproxen
Nonsteroidal anti-inflammatory drug (NSAID)
Brands: Aleve, Naprosyn
View Naproxen safety profileCheck these against your full medication list in our free Interaction Checker
This information is educational — not medical advice.
This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.
Other Meloxicam Interactions
- Meloxicam + Aspirin(contraindicated)
- Meloxicam + Cyclosporine(moderate)
- Meloxicam + Methotrexate(moderate)
- Meloxicam + Warfarin(moderate)
- Meloxicam + Celecoxib(minor)
- Meloxicam + Fluconazole(minor)
- Meloxicam + Furosemide(minor)
- Meloxicam + Indomethacin(minor)
- Meloxicam + Itraconazole(minor)
- Meloxicam + Lithium(minor)
- Meloxicam + Propranolol(minor)
Other Naproxen Interactions
- Naproxen + Aspirin(contraindicated)
- Naproxen + Diclofenac(major)
- Naproxen + Indomethacin(major)
- Naproxen + Cyclosporine(moderate)
- Naproxen + Methotrexate(moderate)
- Naproxen + Warfarin(moderate)
- Naproxen + Celecoxib(minor)
- Naproxen + Digoxin(minor)
- Naproxen + Fluconazole(minor)
- Naproxen + Furosemide(minor)
- Naproxen + Gabapentin(minor)
- Naproxen + Ibuprofen(minor)
- Naproxen + Lithium(minor)
- Naproxen + Propranolol(minor)
- Naproxen + Sucralfate(minor)