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    HomeMedication GuideDrug InteractionsAspirin + Meloxicam
    Contraindicated interaction

    Does Aspirin Interact With Meloxicam?

    4 CONTRAINDICATIONS Meloxicam is contraindicated in the following patients: Known hypersensitivity (e.g., anaphylactic reactions and serious skin reactions) to meloxicam or any components of the drug product [see Warnings and Precautions ( 5.7 , 5.9 ) ] History of asthma, urticaria, or other allergic-type reactions after taking aspirin or other NSAIDs.

    Severity: Contraindicated

    Severity basis: contraindications section (keywords: contraindicated). Combining Aspirin (Antiplatelet / NSAID) and Meloxicam (Nonsteroidal anti-inflammatory drug (NSAID)) is classified as a contraindicated interaction.

    What to Do

    This combination is contraindicated on the FDA label. Do not take these together unless your prescriber explicitly directs it.

    From the FDA Label

    4 CONTRAINDICATIONS Meloxicam is contraindicated in the following patients: Known hypersensitivity (e.g., anaphylactic reactions and serious skin reactions) to meloxicam or any components of the drug product [see Warnings and Precautions ( 5.7 , 5.9 ) ] History of asthma, urticaria, or other allergic-type reactions after taking aspirin or other NSAIDs.

    Source: FDA structured product labeling (set_id 06a401f0-4380-4081-86ed-a309a25abf6b).

    Aspirin

    Antiplatelet / NSAID

    Brands: Bayer, Ecotrin, Bufferin

    View Aspirin safety profile

    Meloxicam

    Nonsteroidal anti-inflammatory drug (NSAID)

    Brands: Mobic

    View Meloxicam safety profile

    Check these against your full medication list in our free Interaction Checker

    This information is educational — not medical advice.

    This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.

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