Does Furosemide Interact With Risperidone?
In two of four placebo-controlled trials in elderly patients with dementia-related psychosis, a higher incidence of mortality was observed in patients treated with furosemide plus risperidone tablets when compared to patients treated with risperidone tablets alone or with placebo plus furosemide.
Severity: Minor
Severity basis: warnings section. Combining Furosemide (Loop diuretic) and Risperidone (Atypical antipsychotic) is classified as a minor interaction.
What to Do
This is generally a minor interaction, but review it with your pharmacist to be sure it is safe for you.
From the FDA Label
In two of four placebo-controlled trials in elderly patients with dementia-related psychosis, a higher incidence of mortality was observed in patients treated with furosemide plus risperidone tablets when compared to patients treated with risperidone tablets alone or with placebo plus furosemide.
Source: FDA structured product labeling (set_id 03d3b52d-3a7d-4595-84c9-332da6ca9171).
Check these against your full medication list in our free Interaction Checker
This information is educational — not medical advice.
This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.
Other Furosemide Interactions
- Furosemide + Cyclosporine(moderate)
- Furosemide + Indomethacin(moderate)
- Furosemide + Methotrexate(moderate)
- Furosemide + Phenytoin(moderate)
- Furosemide + Sucralfate(moderate)
- Furosemide + Aspirin(minor)
- Furosemide + Atenolol(minor)
- Furosemide + Celecoxib(minor)
- Furosemide + Levothyroxine(minor)
- Furosemide + Liothyronine(minor)
- Furosemide + Lithium(minor)
- Furosemide + Meloxicam(minor)
- Furosemide + Naproxen(minor)
- Furosemide + Potassium Chloride(minor)
- Furosemide + Ramipril(minor)
- Furosemide + Tamsulosin(minor)
Other Risperidone Interactions
- Risperidone + Amitriptyline(major)
- Risperidone + Carbamazepine(moderate)
- Risperidone + Carbidopa Levodopa(moderate)
- Risperidone + Itraconazole(moderate)
- Risperidone + Methylphenidate(moderate)
- Risperidone + Bupropion(minor)
- Risperidone + Digoxin(minor)
- Risperidone + Fluoxetine(minor)
- Risperidone + Lithium(minor)
- Risperidone + Paroxetine(minor)
- Risperidone + Quetiapine(minor)
- Risperidone + Valproic Acid(minor)
- Risperidone + Venlafaxine(minor)