Does Furosemide Interact With Lithium?
Lithium generally should not be given with diuretics because they reduce lithium's renal clearance and add a high risk of lithium toxicity.
Severity: Minor
Severity basis: drug interactions section. Combining Furosemide (Loop diuretic) and Lithium (Mood stabilizer) is classified as a minor interaction.
What to Do
This is generally a minor interaction, but review it with your pharmacist to be sure it is safe for you.
From the FDA Label
Lithium generally should not be given with diuretics because they reduce lithium's renal clearance and add a high risk of lithium toxicity.
Source: FDA structured product labeling (set_id 01a5f094-b473-4e46-9e61-69d5ec6dd766).
Check these against your full medication list in our free Interaction Checker
This information is educational — not medical advice.
This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.
Other Furosemide Interactions
- Furosemide + Cyclosporine(moderate)
- Furosemide + Indomethacin(moderate)
- Furosemide + Methotrexate(moderate)
- Furosemide + Phenytoin(moderate)
- Furosemide + Sucralfate(moderate)
- Furosemide + Aspirin(minor)
- Furosemide + Atenolol(minor)
- Furosemide + Celecoxib(minor)
- Furosemide + Levothyroxine(minor)
- Furosemide + Liothyronine(minor)
- Furosemide + Meloxicam(minor)
- Furosemide + Naproxen(minor)
- Furosemide + Potassium Chloride(minor)
- Furosemide + Ramipril(minor)
- Furosemide + Risperidone(minor)
- Furosemide + Tamsulosin(minor)
Other Lithium Interactions
- Lithium + Olanzapine(contraindicated)
- Lithium + Amiodarone(moderate)
- Lithium + Aripiprazole(moderate)
- Lithium + Benazepril(moderate)
- Lithium + Canagliflozin(moderate)
- Lithium + Carbamazepine(moderate)
- Lithium + Dapagliflozin(moderate)
- Lithium + Empagliflozin(moderate)
- Lithium + Fluoxetine(moderate)
- Lithium + Hydrochlorothiazide(moderate)
- Lithium + Insulin Aspart(moderate)
- Lithium + Insulin Glargine(moderate)
- Lithium + Lisinopril(moderate)
- Lithium + Metronidazole(moderate)
- Lithium + Phenytoin(moderate)
- Lithium + Ramipril(moderate)
- Lithium + Spironolactone(moderate)
- Lithium + Topiramate(moderate)
- Lithium + Valsartan(moderate)
- Lithium + Amphetamine Dextroamphetamine(minor)
- Lithium + Buspirone(minor)
- Lithium + Celecoxib(minor)
- Lithium + Citalopram(minor)
- Lithium + Desvenlafaxine(minor)
- Lithium + Duloxetine(minor)
- Lithium + Enalapril(minor)
- Lithium + Escitalopram(minor)
- Lithium + Indomethacin(minor)
- Lithium + Irbesartan(minor)
- Lithium + Lisdexamfetamine(minor)
- Lithium + Losartan(minor)
- Lithium + Meloxicam(minor)
- Lithium + Mirtazapine(minor)
- Lithium + Naproxen(minor)
- Lithium + Nortriptyline(minor)
- Lithium + Olmesartan(minor)
- Lithium + Ondansetron(minor)
- Lithium + Paroxetine(minor)
- Lithium + Quetiapine(minor)
- Lithium + Risperidone(minor)
- Lithium + Sertraline(minor)
- Lithium + Telmisartan(minor)
- Lithium + Tramadol(minor)
- Lithium + Trazodone(minor)
- Lithium + Valproic Acid(minor)
- Lithium + Venlafaxine(minor)
- Lithium + Verapamil(minor)