Does Lovastatin Interact With Testosterone?

However, clinical studies have shown that lovastatin does not reduce basal plasma cortisol concentration or impair adrenal reserve, and does not reduce basal plasma testosterone concentration.

Severity: Minor

Severity basis: drug interactions section. Combining Lovastatin (HMG-CoA reductase inhibitor (statin)) and Testosterone (Androgen (testosterone replacement)) is classified as a minor interaction.

What to Do

This is generally a minor interaction, but review it with your pharmacist to be sure it is safe for you.

From the FDA Label

However, clinical studies have shown that lovastatin does not reduce basal plasma cortisol concentration or impair adrenal reserve, and does not reduce basal plasma testosterone concentration.

Source: FDA structured product labeling (set_id 027bd594-6a0a-4e6d-bd3c-4f33fdb4166a).

Lovastatin

HMG-CoA reductase inhibitor (statin)

Brands: Mevacor, Altoprev

View Lovastatin safety profile

Testosterone

Androgen (testosterone replacement)

Brands: Depo-Testosterone, Xyosted

View Testosterone safety profile

Check these against your full medication list in our free Interaction Checker

This information is educational — not medical advice.

This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.

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