Does Lovastatin Interact With Warfarin?

Coumarin Anticoagulants In a small clinical trial in which lovastatin was administered to warfarin treated patients, no effect on prothrombin time was detected.

Severity: Minor

Severity basis: drug interactions section. Combining Lovastatin (HMG-CoA reductase inhibitor (statin)) and Warfarin (Vitamin K antagonist anticoagulant) is classified as a minor interaction.

What to Do

This is generally a minor interaction, but review it with your pharmacist to be sure it is safe for you.

From the FDA Label

Coumarin Anticoagulants In a small clinical trial in which lovastatin was administered to warfarin treated patients, no effect on prothrombin time was detected.

Source: FDA structured product labeling (set_id 027bd594-6a0a-4e6d-bd3c-4f33fdb4166a).

Lovastatin

HMG-CoA reductase inhibitor (statin)

Brands: Mevacor, Altoprev

View Lovastatin safety profile

Warfarin

Vitamin K antagonist anticoagulant

Brands: Coumadin, Jantoven

View Warfarin safety profile

Check these against your full medication list in our free Interaction Checker

This information is educational — not medical advice.

This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.

Questions About Your Medications?

A licensed OmniRx provider can review your full medication list and help you understand what's safe for you — no office visit required.