Does Diazepam Interact With Olanzapine?

Diazepam: May potentiate orthostatic hypotension.

Severity: Moderate

Severity basis: drug interactions section (keywords: may potentiate). Combining Diazepam (Benzodiazepine) and Olanzapine (Atypical antipsychotic) is classified as a moderate interaction.

What to Do

Use this combination with caution. Your prescriber may monitor you more closely or adjust doses.

From the FDA Label

Diazepam: May potentiate orthostatic hypotension.

Source: FDA structured product labeling (set_id 002dd00f-7946-ea4f-e063-6294a90a5916).

Diazepam

Benzodiazepine

Brands: Valium

View Diazepam safety profile

Olanzapine

Atypical antipsychotic

Brands: Zyprexa

View Olanzapine safety profile

Check these against your full medication list in our free Interaction Checker

This information is educational — not medical advice.

This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.

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