Does Tadalafil Interact With Tamsulosin?
Clinical pharmacology studies have been conducted with coadministration of tadalafil with doxazosin, tamsulosin or alfuzosin.
Severity: Minor
Severity basis: drug interactions section. Combining Tadalafil (PDE5 inhibitor) and Tamsulosin (Alpha-1 blocker (BPH)) is classified as a minor interaction.
What to Do
This is generally a minor interaction, but review it with your pharmacist to be sure it is safe for you.
From the FDA Label
Clinical pharmacology studies have been conducted with coadministration of tadalafil with doxazosin, tamsulosin or alfuzosin.
Source: FDA structured product labeling (set_id 00cbc656-768d-4995-bb6d-a0d4b32a248c).
Check these against your full medication list in our free Interaction Checker
This information is educational — not medical advice.
This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.
Other Tadalafil Interactions
- Tadalafil + Isosorbide Mononitrate(contraindicated)
- Tadalafil + Nitroglycerin(contraindicated)
- Tadalafil + Itraconazole(major)
- Tadalafil + Carbamazepine(moderate)
- Tadalafil + Clarithromycin(moderate)
- Tadalafil + Amlodipine(minor)
- Tadalafil + Aspirin(minor)
- Tadalafil + Digoxin(minor)
- Tadalafil + Enalapril(minor)
- Tadalafil + Ketoconazole(minor)
- Tadalafil + Lovastatin(minor)
- Tadalafil + Metoprolol(minor)
- Tadalafil + Phenytoin(minor)
- Tadalafil + Rifampin(minor)
- Tadalafil + Warfarin(minor)