Does Amphetamine Dextroamphetamine Interact With Tramadol?

This is generally a minor interaction, but review it with your pharmacist to be sure it is safe for you.

Interactions like this one can happen when two medicines have overlapping effects, or when one changes how the other is absorbed, broken down, or cleared from the body. Amphetamine Dextroamphetamine is a cns stimulant (adhd) and Tramadol is a opioid analgesic; together they are documented as a minor interaction. How much this matters depends on your dose, your other medications, and your overall health.

If you have been prescribed both Amphetamine Dextroamphetamine and Tramadol, do not start, stop, or change either medication on your own — some medicines are unsafe to stop suddenly. Tell your prescriber and pharmacist that you take both so they can decide whether the combination is right for you, adjust the dose, monitor you more closely, or suggest an alternative.

5.8 Serotonin Syndrome Serotonin syndrome, a potentially life-threatening reaction, may occur when amphetamines are used in combination with other drugs that affect the serotonergic neurotransmitter systems such as MAOIs, selective serotonin reuptake inhibitors (SSRIs), serotonin norepinephrine reuptake inhibitors (SNRIs), triptans, tricyclic antidepressants, fentanyl, lithium, tramadol, tryptophan, buspirone, and St.

Source: FDA structured product labeling (set_id aff45863-ffe1-4d4f-8acf-c7081512a6c0).