Does Amiodarone Interact With Carvedilol?

( 7.4 ) Amiodarone may increase carvedilol levels resulting in further slowing of the heart rate or cardiac conduction.

Severity: Moderate

Severity basis: drug interactions section (keywords: may increase). Combining Amiodarone (Class III antiarrhythmic) and Carvedilol (Beta-blocker) is classified as a moderate interaction.

What to Do

Use this combination with caution. Your prescriber may monitor you more closely or adjust doses.

From the FDA Label

( 7.4 ) Amiodarone may increase carvedilol levels resulting in further slowing of the heart rate or cardiac conduction.

Source: FDA structured product labeling (set_id 010290af-81f4-0037-e063-6394a90a4638).

Amiodarone

Class III antiarrhythmic

Brands: Pacerone, Cordarone

View Amiodarone safety profile

Carvedilol

Beta-blocker

Brands: Coreg

View Carvedilol safety profile

Check these against your full medication list in our free Interaction Checker

This information is educational — not medical advice.

This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.

Questions About Your Medications?

A licensed OmniRx provider can review your full medication list and help you understand what's safe for you — no office visit required.