Does Dicyclomine Interact With Digoxin?

7.5 Effect on Absorption of Other Drugs Anticholinergic agents may affect gastrointestinal absorption of various drugs by affecting on gastrointestinal motility, such as slowly dissolving dosage forms of digoxin; increased serum digoxin concentration may result.

Severity: Minor

Severity basis: drug interactions section. Combining Dicyclomine (Antispasmodic (anticholinergic)) and Digoxin (Cardiac glycoside) is classified as a minor interaction.

What to Do

This is generally a minor interaction, but review it with your pharmacist to be sure it is safe for you.

From the FDA Label

7.5 Effect on Absorption of Other Drugs Anticholinergic agents may affect gastrointestinal absorption of various drugs by affecting on gastrointestinal motility, such as slowly dissolving dosage forms of digoxin; increased serum digoxin concentration may result.

Source: FDA structured product labeling (set_id 01413a77-48f8-1a8a-e063-6394a90ae494).

Dicyclomine

Antispasmodic (anticholinergic)

Brands: Bentyl

View Dicyclomine safety profile

Digoxin

Cardiac glycoside

Brands: Lanoxin

View Digoxin safety profile

Check these against your full medication list in our free Interaction Checker

This information is educational — not medical advice.

This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.

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Other Dicyclomine Interactions

Dicyclomine + Metoclopramide(minor)