Does Digoxin Interact With Verapamil?

( Note interactions with digoxin under PRECAUTIONS .) Hypotension: Occasionally, the pharmacologic action of verapamil may produce a decrease in blood pressure below normal levels, which may result in dizziness or symptomatic hypotension.

Severity: Moderate

Severity basis: warnings section (keywords: caution). Combining Digoxin (Cardiac glycoside) and Verapamil (Calcium channel blocker) is classified as a moderate interaction.

What to Do

Use this combination with caution. Your prescriber may monitor you more closely or adjust doses.

From the FDA Label

( Note interactions with digoxin under PRECAUTIONS .) Hypotension: Occasionally, the pharmacologic action of verapamil may produce a decrease in blood pressure below normal levels, which may result in dizziness or symptomatic hypotension.

Source: FDA structured product labeling (set_id 006cf920-04ae-0b53-cb91-85481972abc2).

Digoxin

Cardiac glycoside

Brands: Lanoxin

View Digoxin safety profile

Verapamil

Calcium channel blocker

Brands: Calan, Verelan

View Verapamil safety profile

Check these against your full medication list in our free Interaction Checker

This information is educational — not medical advice.

This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.

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