Does Carbamazepine Interact With Dabigatran?

Concomitant use of carbamazepine with rivaroxaban, apixaban, dabigatran, and edoxaban (direct acting oral anticoagulants) is expected to result in decreased plasma concentration of these anticoagulants that may be insufficient to achieve the intended therapeutic effect.

Severity: Minor

Severity basis: drug interactions section. Combining Carbamazepine (Anticonvulsant) and Dabigatran (Direct thrombin inhibitor) is classified as a minor interaction.

What to Do

This is generally a minor interaction, but review it with your pharmacist to be sure it is safe for you.

From the FDA Label

Concomitant use of carbamazepine with rivaroxaban, apixaban, dabigatran, and edoxaban (direct acting oral anticoagulants) is expected to result in decreased plasma concentration of these anticoagulants that may be insufficient to achieve the intended therapeutic effect.

Source: FDA structured product labeling (set_id 047bc284-060a-4db9-bf37-75d10f95a0a6).

Carbamazepine

Anticonvulsant

Brands: Tegretol, Carbatrol

View Carbamazepine safety profile

Dabigatran

Direct thrombin inhibitor

Brands: Pradaxa

View Dabigatran safety profile

Check these against your full medication list in our free Interaction Checker

This information is educational — not medical advice.

This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.

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