Does Carbamazepine Interact With Gabapentin?

Carbamazepine Steady-state trough plasma carbamazepine and carbamazepine 10, 11 epoxide concentrations were not affected by concomitant gabapentin (400 mg three times a day; N=12) administration.

Severity: Minor

Severity basis: drug interactions section. Combining Carbamazepine (Anticonvulsant) and Gabapentin (Gabapentinoid anticonvulsant) is classified as a minor interaction.

What to Do

This is generally a minor interaction, but review it with your pharmacist to be sure it is safe for you.

From the FDA Label

Carbamazepine Steady-state trough plasma carbamazepine and carbamazepine 10, 11 epoxide concentrations were not affected by concomitant gabapentin (400 mg three times a day; N=12) administration.

Source: FDA structured product labeling (set_id 01b810b7-f4c8-4412-bbc5-b9220d8770d8).

Carbamazepine

Anticonvulsant

Brands: Tegretol, Carbatrol

View Carbamazepine safety profile

Gabapentin

Gabapentinoid anticonvulsant

Brands: Neurontin, Gralise

View Gabapentin safety profile

Check these against your full medication list in our free Interaction Checker

This information is educational — not medical advice.

This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.

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