Does Amiodarone Interact With Atenolol?

Amiodarone is an antiarrhythmic agent with negative chronotropic properties that may be additive to those seen with beta-blockers.

Severity: Minor

Severity basis: drug interactions section. Combining Amiodarone (Class III antiarrhythmic) and Atenolol (Beta-blocker) is classified as a minor interaction.

What to Do

This is generally a minor interaction, but review it with your pharmacist to be sure it is safe for you.

From the FDA Label

Amiodarone is an antiarrhythmic agent with negative chronotropic properties that may be additive to those seen with beta-blockers.

Source: FDA structured product labeling (set_id 09b21985-1818-449d-9b29-98f733cf7b9f).

Amiodarone

Class III antiarrhythmic

Brands: Pacerone, Cordarone

View Amiodarone safety profile

Atenolol

Beta-blocker

Brands: Tenormin

View Atenolol safety profile

Check these against your full medication list in our free Interaction Checker

This information is educational — not medical advice.

This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.

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