Does Amiodarone Interact With Prednisone?

Prednisone 40 to 60 mg/day tapered over several weeks may be helpful in treating pulmonary toxicity.

Severity: Minor

Severity basis: warnings section. Combining Amiodarone (Class III antiarrhythmic) and Prednisone (Systemic corticosteroid) is classified as a minor interaction.

What to Do

This is generally a minor interaction, but review it with your pharmacist to be sure it is safe for you.

From the FDA Label

Prednisone 40 to 60 mg/day tapered over several weeks may be helpful in treating pulmonary toxicity.

Source: FDA structured product labeling (set_id 02f4a736-63ed-4ad4-a1f1-b21a71e928bd).

Amiodarone

Class III antiarrhythmic

Brands: Pacerone, Cordarone

View Amiodarone safety profile

Prednisone

Systemic corticosteroid

Brands: Deltasone, Rayos

View Prednisone safety profile

Check these against your full medication list in our free Interaction Checker

This information is educational — not medical advice.

This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.

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