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    HomeMedication GuideDrug InteractionsClarithromycin + Quetiapine
    Major interaction

    Does Clarithromycin Interact With Quetiapine?

    Colchicine (in patients with normal renal and hepatic function) Use With Caution Antipsychotics: Pimozide Contraindicated Pimozide: [See Contraindications ( 4.2 )] Quetiapine Lurasidone Quetiapine: Quetiapine is a substrate for CYP3A4, which is inhibited by clarithromycin.

    Severity: Major

    Severity basis: drug interactions section (keywords: contraindicated). Combining Clarithromycin (Macrolide antibiotic) and Quetiapine (Atypical antipsychotic) is classified as a major interaction.

    What to Do

    The label advises avoiding this combination or using it only under close medical supervision. Talk to your prescriber or pharmacist before combining them.

    From the FDA Label

    Colchicine (in patients with normal renal and hepatic function) Use With Caution Antipsychotics: Pimozide Contraindicated Pimozide: [See Contraindications ( 4.2 )] Quetiapine Lurasidone Quetiapine: Quetiapine is a substrate for CYP3A4, which is inhibited by clarithromycin.

    Source: FDA structured product labeling (set_id 0be243c6-de02-45dd-8210-cab1bbc8dfa7).

    Clarithromycin

    Macrolide antibiotic

    Brands: Biaxin

    View Clarithromycin safety profile

    Quetiapine

    Atypical antipsychotic

    Brands: Seroquel

    View Quetiapine safety profile

    Check these against your full medication list in our free Interaction Checker

    This information is educational — not medical advice.

    This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.

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    Other Clarithromycin Interactions