Trusted by over 10K subscribers
    Free & discreet shipping on all prescriptions
    Affordable pricing with no hidden fees
    FDA-regulated pharmacies
    100% online process
    Trusted by over 10K subscribers
    Free & discreet shipping on all prescriptions
    Affordable pricing with no hidden fees
    FDA-regulated pharmacies
    100% online process
    Trusted by over 10K subscribers
    Free & discreet shipping on all prescriptions
    Affordable pricing with no hidden fees
    FDA-regulated pharmacies
    100% online process
    HomeMedication GuideDrug InteractionsRifampin + Ticagrelor
    Major interaction

    Does Rifampin Interact With Ticagrelor?

    Avoid use with strong inducers of CYP3A (e.g., rifampin, phenytoin, carbamazepine and phenobarbital) [see Clinical Pharmacology ( 12.3) ].

    Severity: Major

    Severity basis: drug interactions section (keywords: avoid). Combining Rifampin (Rifamycin antibiotic (strong CYP3A4 inducer)) and Ticagrelor (P2Y12 antiplatelet) is classified as a major interaction.

    What to Do

    The label advises avoiding this combination or using it only under close medical supervision. Talk to your prescriber or pharmacist before combining them.

    From the FDA Label

    Avoid use with strong inducers of CYP3A (e.g., rifampin, phenytoin, carbamazepine and phenobarbital) [see Clinical Pharmacology ( 12.3) ].

    Source: FDA structured product labeling (set_id 1225fd45-9b56-1671-ee77-cd0c9f2174a5).

    Rifampin

    Rifamycin antibiotic (strong CYP3A4 inducer)

    Brands: Rifadin

    View Rifampin safety profile

    Ticagrelor

    P2Y12 antiplatelet

    Brands: Brilinta

    View Ticagrelor safety profile

    Check these against your full medication list in our free Interaction Checker

    This information is educational — not medical advice.

    This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.

    Questions About Your Medications?

    A licensed OmniRx provider can review your full medication list and help you understand what's safe for you — no office visit required.

    Other Rifampin Interactions