Does Insulin Aspart Interact With Lithium?

Drugs That May Increase or Decrease the Blood Glucose Lowering Effect of NOVOLOG Drugs: Alcohol, beta-blockers, clonidine, and lithium salts.

Severity: Moderate

Severity basis: drug interactions section (keywords: may increase). Combining Insulin Aspart (Rapid-acting insulin) and Lithium (Mood stabilizer) is classified as a moderate interaction.

What to Do

Use this combination with caution. Your prescriber may monitor you more closely or adjust doses.

From the FDA Label

Drugs That May Increase or Decrease the Blood Glucose Lowering Effect of NOVOLOG Drugs: Alcohol, beta-blockers, clonidine, and lithium salts.

Source: FDA structured product labeling (set_id 13891e5a-e57a-46e8-911c-2f680352b52b).

Insulin Aspart

Rapid-acting insulin

Brands: NovoLog, Fiasp

View Insulin Aspart safety profile

Lithium

Mood stabilizer

Brands: Lithobid, Eskalith

View Lithium safety profile

Check these against your full medication list in our free Interaction Checker

This information is educational — not medical advice.

This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.

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