Does Gemfibrozil Interact With Warfarin?

Concomitant Anticoagulants-Caution should be exercised when warfarin is given in conjunction with gemfibrozil.

Severity: Moderate

Severity basis: warnings section (keywords: caution). Combining Gemfibrozil (Fibrate) and Warfarin (Vitamin K antagonist anticoagulant) is classified as a moderate interaction.

What to Do

Use this combination with caution. Your prescriber may monitor you more closely or adjust doses.

From the FDA Label

Concomitant Anticoagulants-Caution should be exercised when warfarin is given in conjunction with gemfibrozil.

Source: FDA structured product labeling (set_id 05bfbcdc-03ab-4fba-9582-980602410ef9).

Gemfibrozil

Fibrate

Brands: Lopid

View Gemfibrozil safety profile

Warfarin

Vitamin K antagonist anticoagulant

Brands: Coumadin, Jantoven

View Warfarin safety profile

Check these against your full medication list in our free Interaction Checker

This information is educational — not medical advice.

This page is provided for general educational purposes and summarizes publicly available data from sources such as the U.S. Food & Drug Administration. It is not a substitute for the judgment of a licensed clinician and should not be used to start, stop, or change any medication. It may be incomplete or out of date, and individual circumstances vary. Always talk with your prescriber or pharmacist about your specific medications and health conditions. If you think you may have a medical emergency, call 911.

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